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In Vivo Studies on Radiofrequency (100 kHz–300 GHz) Electromagnetic Field Exposure and Cancer: A Systematic Review

TitleIn Vivo Studies on Radiofrequency (100 kHz–300 GHz) Electromagnetic Field Exposure and Cancer: A Systematic Review
Publication TypeArticolo su Rivista peer-reviewed
Year of Publication2023
AuthorsPinto, Rosanna, Ardoino L., Villani Paola, and Marino Carmela
JournalInternational Journal of Environmental Research and Public Health
Volume20
ISSN16617827
Abstract

The increasing exposure of the human population to radiofrequency electromagnetic fields has increased concern about its possible health effects. The aim of this systematic review is to provide an update of the state of the research on this topic, through a quantitative analysis, to assess the increased risk of tumor incidence in laboratory animals (rodents) without limitations of species, strain, sex or genotype. The review was conducted according to the PRISMA guideline and individual studies were assessed by referring to the OHAT Risk of Bias Rating Tool for Human and Animal Studies. A total of 27 studies were considered eligible for the evaluation of tumor incidence; a meta-analysis was carried out on 23 studies to assess the possible increased risk of both malignant and benign tumors onset at the systemic level or in different organs/tissues. A significant association between exposure to RF and the increased/decreased risk of cancer does not result from the meta-analysis in most of considered tissues. A significant increased/decreased risk can be numerically observed only in heart, CNS/brain, and intestine for malignant tumors. Nevertheless, the assessment of the body of evidence attributes low or inadequate evidence for an association between RF exposure and the onset of neoplasm in all tissues. © 2023 by the authors.

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URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85147859347&doi=10.3390%2fijerph20032071&partnerID=40&md5=e7c6749cd88a468ac3c64b2a486aab2c
DOI10.3390/ijerph20032071
Citation KeyPinto2023