Laboratory Biomedical Technologies
TEB Laboratory performs multidisciplinary research in classic and molecular radiobiology, experimental oncology and carcinogenesis, molecular immunology, molecular basis of chronic inflammatory diseases, biological effects and clinical applications of electromagnetic fields, and on the use of natural compounds for human and animal health protection.
The laboratory pursues the study of low-dose ionizing radiation effects, specifically regarding the risk esteem from environmental, cosmic, occupational and medical exposure. Moreover, cellular and molecular mechanisms related to cancer and non-cancer effects of radiation are evaluated, developing radiation high-sensitivity animal models, as well as specific in vitro models, in order to improve low-dose exposure risk quantification.
Research on thermal and non-thermal effects of electromagnetic fields are carried out, along with design and development of experimental models and exposure systems, therapeutic and diagnostic applications, besides the evaluation of exposure standards related to general population and occupational health protection.
The laboratory is involved in the study of immune response regulatory mechanisms, so as to identify new therapeutic targets, understand environmental factors’ effects, characterize the alterations responsible for immune-mediate disorders (autoimmunity, allergies, inflammatory diseases). By the integration of in vivo and in vitro models, experimental protocols and innovative immune-therapeutic tools for cancer therapy, vaccines and chronic inflammatory diseases’ diagnosis and treatment are developed.
Furthermore, a specific research line analyzes the role of a natural plant extract in inflammatory and repair processes involved in wound healing.
Research topics
Projects
Status: In corso
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Scientific-Based Exposure and Risk Assessment of Radiofrequency and mm-Wave Systems from children to elderly (5G and Beyond)
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Partnership for european research in radiation protection and detection of ionising radiation: towards a safer use and improved protection of the environment and human health.
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Dosimetria di un nuovo trattamento rTMS in colture 3D della malattia di Alzheimer per l’identificazione di marcatori di efficacia terapeutica
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Indagine, tramite questionario, sulle correlazioni tra le reazioni avverse post-vaccinali al vaccino anti Covid-19 e le abitudini alimentari, lo stile di vita e l'anamnesi personale e familiare
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Plant virus nanoparticles for blood-brain barrier crossing and medulloblastoma targeting
Status: Concluso
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HEXEDRA safety study
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Effects of the exposure of young animals to radiofrequencies
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Evaluation of the pharmacological efficacy of the ST1959 synthesis molecule in mouse models of Graft Versus Host Disease (GVHD)
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Assement of the opsonizing activty of PTX3 on conidia from the opportunistic pathogen A. fumigatus
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Assessment of the activity of biological and biothecnological products through immunological assays
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Systemic Effects of Partial-body Exposure to Low Radiation Doses
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New therapeutic strategy for medulloblastoma: targeting cancer stem cells to promote differentiantion and radiosensitization
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Semiconductor-based Ultrawideband Micromanipulation of CAncer STEm Cells
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Towards a full mechanistic understanding of low dose radiation induced cataracts
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Personalizing radiation therapy: an experimental model to dissect genetics of radiation-induced skin fibrosis
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Studio, validazione e realizzazione di un nuovo kit per la diagnosi precoce delle infiammazioni intestinali tramite utilizzo della proteina hmgb1 come marcatore fecale
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Molecular study of pathogenetic mechanisms underlying the intestinal inflammatory diseases
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Open Project for the European Radiation Research Area: SOPRANO project 'System Oriented Prediction of Radiation Risk'
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Cardiovascular Risk from Exposure to Low-dose and Low-dose-rate Ionizing Radiation
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Cognitive and Cerebrovascular Effects Induced by Low Dose Ionising Radiation
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Studies on a cohort of Serbian children exposed to x-irradiation to determine the contribution of the non-coding genome to susceptibility at low doses
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Low dose research towards multidisciplinary integration
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European Joint Programme for the Integration of Radiation Protection Research
